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Ascletis Pharma Inc. (ASCLF)

NEGATIVE
HealthcareBiotechnologyHong Kong

Fondamental

27

Prix

$9.88

Capitalisation boursière

$10.11B

Partie 1 · Ce que vaut l'entreprise

Vue d'ensemble

Ascletis Pharma is a Hangzhou-based Chinese biotech that develops and, on a small scale, sells drugs. It already markets treatments for hepatitis C, including Ganovo and a ritonavir tablet, in China, but that legacy business generates only minimal revenue. The company has pivoted most of its research toward metabolic disease — obesity and fatty liver — with pipeline candidates like ASC30 and ASC41, and it has also licensed in a China-market NASH drug, denifanstat, from a US partner.

Comment l'entreprise gagne de l'argent

Ascletis earns a small amount of revenue selling its approved hepatitis C drugs in China, but this legacy business is not the point of the company today: most of the value investors are pricing in depends on drug candidates still in clinical trials that generate no revenue at all. Until a metabolic-disease drug such as ASC30 or ASC41 is approved and launched, Ascletis is funded mainly by capital raised from investors rather than by product sales.

Les arguments en faveur

Buyers argue that early obesity data — a Phase 2 US study reported 7.7% weight loss for its oral GLP-1 candidate — puts Ascletis in one of the most closely watched drug categories in the industry, and that its established, revenue-generating hepatitis C franchise shows the company can already get drugs through Chinese regulators and to market.

Les arguments contre

Sellers worry that Ascletis' actual product revenue is still minimal, that its valuation rests almost entirely on obesity and metabolic-disease candidates years away from approval in a field crowded with better-funded rivals, and that its pivot away from the older hepatitis C business leaves little near-term commercial base to fall back on.

Written by the editors, published on 18 août 2026

Direct competitors

Who this company fights with for the same customers

Compare

Generated on 23 août 2026 with claude-opus-5 — shared with all users

P/E: —Score: 51Market cap: $3.84B

Viking's oral VK2735 tablet targets the same obesity patients with the same oral-pill format, making it the other emerging-biotech contender competing with ASC30 for prescriptions and for a partner or acquirer.

P/E: 41.8Score: 76Market cap: $1.18T

Lilly's orforglipron is the oral small molecule GLP-1 that Ascletis explicitly benchmarks ASC30 against on weight loss and tolerability, and its amylin agonist eloralintide competes head-on with Ascletis' ASC39.

P/E: 11.4Score: 66Market cap: $1.01T

Novo Nordisk defends the obesity market Ascletis is trying to enter, with oral semaglutide and the oral candidate amycretin aimed at exactly the same overweight and type 2 diabetes patients.

Structure Therapeutics Inc.GPCR

Both are clinical-stage biotechs whose entire value rests on a once-daily oral small molecule GLP-1 agonist for chronic weight management, with Structure's aleniglipron and Ascletis' ASC30 running competing global Phase III obesity programmes.

Jiangsu Hengrui Pharmaceuticals Co., Ltd. (江苏恒瑞医药股份有限公司)600276.SS

Hengrui's HRS-7535 is the Chinese oral small molecule GLP-1 furthest ahead in obesity and type 2 diabetes, competing with ASC30 both for Chinese patients and for out-licensing deals with Western partners.

Innovent Biologics, Inc. (信達生物製藥)1801.HK

Innovent's mazdutide is already the reference weight-loss therapy in China and is the incumbent ASC30 would have to displace in Ascletis' home market.

Bilan & Liquidités

Chiffre d'affaires

$2M

12 derniers mois jusqu'au dernier trimestre publié — estimation à partir de ratios par action

Résultat net

$-387M

12 derniers mois jusqu'au dernier trimestre publié — estimation à partir de ratios par action

Flux de trésorerie libre

$-300M

Capitaux propres totaux

$2.39B

Passif total

$5M

Ratio de liquidité général

15.05

Couverture des intérêts

-

Dette/EBITDA

-

Bénéfice par action

Chiffre d'affaires & Résultat net

Flux de trésorerie libre

Décomposition du résultat

État historique

Marges dans le temps

La dette dans le temps

Le poids de la dette

Grille de la croissance

Croissance — Chiffre d'affaires

Estimation de la juste valeur

Sous-évalué

Juste valeur

$23.97

Prix actuel

$9.88

Marge de sécurité

+58.8%

Fourchette de juste valeur

$22.77 - $25.17

Méthodes d'estimation

Analyst Target:$23.97
DCF:-
PE-based:-
Graham Growth:-
EPV:-
Consensus des analystes:Achat fort (7B / 2H / 0S)

Indicateurs de valorisation

Ratio P/E

-

ROE

-18.5%

Ratio P/B

4.93

P/FCF

-

Marge brute

26.0%

ROIC

-20.8%

Radar de rentabilité

Value Creation (Economic Moat)

ROIC

-20.8%

WACC

8.0%

ROIC − WACC

-28.7 pp

ROIC is below the cost of capital — the company is destroying value for every dollar invested.

Critères d'analyse fondamentale

Réussi (5)

  • Price CAGR 5.62%
  • Debt/Equity ratio
  • Current Ratio
  • Analyst Consensus 78% Buy
  • Net Margin Trend -17745.6% vs -23455.7%

Échoué (9)

  • ROIC -20.8%
  • Gross Margin 26.0%
  • P/B Ratio 4.93
  • Operating Margin -17712.5%
  • Positive Free Cash Flow
  • DCF valuation (Unknown)
  • ROE -18.9%
  • Revenue Growth 5Y -43.4%
  • Piotroski F-Score 0/9

Indisponible (13)

  • EPS data insufficient
  • P/FCF NaN
  • Dividend Payout NaN%
  • CapEx intensity
  • Interest Coverage
  • Debt/EBITDA
  • Return on Tangible Assets
  • Low reliance on intangibles
  • Price below Graham Number
  • Earnings Surprise (Finnhub)
  • PEG Ratio (need PE > 0 and growth > 0)
  • Earnings Quality (OCF/Net Income)
  • Share Dilution (missing shares data)

Score F de Piotroski

0/9

Préoccupations financières sérieuses

score
criteria

Qualité des bénéfices

-

Qualité faible : examiner la comptabilité

Dilution du capital

-

Rachat d'actions. Favorable aux actionnaires

Gouvernance

Équipe dirigeante

NomTitreÂge
Dr. Jinzi Wu Ph.D.Founder, Chairman & CEO62
Ms. Hejingdao WuSenior VP of Operations & Executive Director51
Dr. Kristjan Sigurdur GudmundssonSenior Consultant & Head of Discovery57
Dr. George Zhengzhi HillSenior Consultant & Chief Medical Advisor74
Mr. John P. Gargiulo M.B.A.Chief Business Officer65
Mr. Ming Fai Chung CPACompany Secretary46

Partie 2 · Le prix et le moment d'entrer

Cette partie ne dit pas si l'entreprise vaut la peine : elle aide à choisir quand l'acheter, une fois que les fondamentaux vous ont convaincu. À l'intérieur : analyse technique, potentiel, baisses historiques, exposition gamma.

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