Amgen Inc. (AMGN)
POSITIVEファンダメンタル
70
株価
$443.73
時価総額
$239.95B
パート1 · 企業の価値
概要
Amgen discovers, manufactures and sells prescription medicines, mostly biologics — drugs made from living cells rather than synthesized chemicals — for osteoporosis, high cholesterol, inflammatory and autoimmune diseases, cancer and rare diseases. It markets roughly 30 approved products, led by Prolia, Repatha, Otezla and Enbrel, through drug wholesalers and specialty pharmacies to patients mainly in the United States, with a smaller international business. It also makes biosimilars, near-copies of other companies' biologic drugs sold once the originals lose patent protection.
収益の仕組み
Revenue comes from per-unit sales of patented medicines, priced through negotiations with insurers, pharmacy benefit managers and government programmes such as US Medicare, net of large rebates. A drug earns outsized profit while under patent and regulatory exclusivity, then typically loses much of its revenue once biosimilar competitors launch, as has already happened to Enbrel and XGEVA; the company reinvests heavily in research and manufacturing to keep new medicines launching ahead of that pattern.
競争優位性(moat)
特許・ライセンス · 狭いPatents and regulatory exclusivity protect pricing for years after launch, and biologics are harder to copy exactly than simple chemical pills, which slows — but does not stop — biosimilar competition once patents expire. Enbrel and XGEVA are already losing share to biosimilars, showing the advantage is real but time-limited rather than a permanent edge.
需要を左右する要因
ディフェンシブMedicines for chronic and serious diseases are needed regardless of the economic cycle, which makes underlying demand defensive. Growth still depends on new product launches outrunning patent expirations on older drugs, and increasingly on government policy: the US Inflation Reduction Act now lets Medicare negotiate prices directly on some of Amgen's medicines, already forcing a write-down on one product.
主なリスク
- Biosimilar erosion of maturing products — Enbrel and XGEVA sales are already declining as biosimilar competitors launch, and other currently profitable products face the same pattern once their patents expire.
- Government drug-pricing pressure — The Inflation Reduction Act lets US Medicare negotiate prices directly on selected medicines; Otezla has already taken a related impairment charge, and more products could be affected over time.
- Manufacturing concentration — Amgen relies on a limited number of manufacturing facilities for its biologic medicines; a quality issue, natural disaster or regulatory problem at one plant can disrupt supply broadly.
- Clinical and regulatory risk — New medicines must clear clinical trials and regulatory approval before generating any revenue, and pipeline candidates can fail late in development after years of investment.
- Payer and reimbursement pressure — Insurers and pharmacy benefit managers negotiate large rebates and can restrict which of Amgen's medicines they cover, directly affecting how much of a drug's list price the company actually keeps.
強気材料
Buyers argue that a broad portfolio of roughly 30 medicines, several still growing at double-digit rates, gives Amgen enough diversification to absorb the loss of any single ageing product while newer launches and its biosimilars business pick up the slack.
弱気材料
Sellers fear that biosimilar erosion of former blockbusters like Enbrel and XGEVA, growing government pricing pressure under the Inflation Reduction Act, and manufacturing concentrated in a handful of plants make sustaining growth harder than the long product list suggests.
Written by the editors, published on 2026年8月18日
Direct competitors
Who this company fights with for the same customers
Generated on 2026年8月23日 with claude-opus-5 — shared with all users
Lilly's tirzepatide (Zepbound/Mounjaro) and its oral follow-ups occupy the obesity and cardiometabolic market that Amgen is trying to enter with MariTide, and the two also overlap in immunology and bone health.
Regeneron's Praluent is the only other PCSK9 injectable competing with Amgen's Repatha for cholesterol patients, and Dupixent competes with Tezspire in severe asthma.
Novo Nordisk's semaglutide (Wegovy/Ozempic) is the incumbent in the obesity and cardiometabolic market that Amgen's MariTide is designed to take share from.
AbbVie's Skyrizi, Rinvoq and Humira franchise fights Amgen's Enbrel, Otezla and Tezspire for the same rheumatology, dermatology and respiratory prescriptions, while Amgen's Amjevita biosimilar attacks Humira revenue directly.
Bristol Myers Squibb competes with Amgen across haematology and oncology, where its CAR-T therapies rival Blincyto in acute lymphoblastic leukaemia, and in psoriasis where Sotyktu takes patients from Otezla.
Sandoz sells denosumab biosimilars that take Prolia and Xgeva revenue away from Amgen, and its wider biosimilar portfolio competes head-to-head with Amgen's own biosimilar business for the same hospital and payer contracts.
貸借対照表と流動性
売上高
$38.09B
直近12か月(2026/6/30まで)
純利益
$8.74B
直近12か月(2026/6/30まで)
フリーキャッシュフロー
$8.10B
自己資本合計
$8.66B
負債合計
$81.93B
流動比率
1.37
利払い倍率
4.28
負債/EBITDA
4.02
一株当たり利益(EPS)
売上高と純利益
フリーキャッシュフロー
収益内訳
財務推移表
利益率の推移
負債の推移
負債の重さ
成長率グリッド
成長率 — 売上高
適正価値の推定
適正価値
$324.99
現在株価
$443.73
安全マージン
-36.5%
適正価値レンジ
$254.33 - $395.65
推定方法
バリュエーション指標
P/E レシオ
27.58
ROE
89.1%
P/B レシオ
20.53
P/FCF
23.58
粗利益率
69.5%
ROIC
12.9%
収益性レーダー
Value Creation (Economic Moat)
ROIC
12.9%
WACC
7.1%
ROIC − WACC
+5.7 pp
ROIC exceeds the cost of capital — the company is creating value for shareholders.
ファンダメンタル分析基準
合格(20)
- EPS shows upward trend
- EPS CAGR 9.58%
- Price CAGR 11.63%
- ROIC 12.9%
- Gross Margin 69.5%
- P/FCF 23.58
- Operating Margin 30.0%
- Positive Free Cash Flow
- CapEx intensity
- Current Ratio
- Interest Coverage
- Debt/EBITDA
- Return on Tangible Assets
- ROE 89.3%
- Revenue Growth 5Y 7.7%
- Earnings Surprise avg 8.9%
- Earnings Quality (OCF/NI) 1.43
- Share Dilution 0.2%
- Net Margin Trend 23.0% vs 19.0%
- Piotroski F-Score 8/9
不合格(7)
- P/B Ratio 20.53
- Debt/Equity ratio
- Low reliance on intangibles
- Price below Graham Number
- DCF valuation (Overvalued)
- Analyst Consensus 49% Buy
- PEG Ratio 8.82
データなし(1)
- Dividend Payout NaN%
Piotroski F-スコア
財務健全性が高い
利益の質
高品質:利益はキャッシュに裏付けられている
株式希薄化
株式数は安定している
ガバナンス
経営陣
| 氏名 | 役職 | 年齢 |
|---|---|---|
| Mr. Robert A. Bradway | Chairman & CEO | 62 |
| Mr. Peter H. Griffith | Executive VP & CFO | 66 |
| Mr. Murdo Gordon | Executive Vice President of Global Markets and Policy | 58 |
| Dr. James E. Bradner M.D. | EVP of Research & Development, Artificial Intelligence and Data | 53 |
| Mr. Esteban Santos | Executive Vice President of Operations | 57 |
| Mr. Matthew C. Busch | Chief Accounting Officer & VP of Finance | 50 |
| Mr. Sean Bruich | SVP & Chief Technology Officer | - |
| Mr. Scott Skellenger | Senior VP & Chief Information Officer | - |
| Mr. Howard Y. Chang M.D., Ph.D. | Senior VP of Global Research & Chief Scientific Officer | - |
| Casey Capparelli | Executive Director of Investor Relations | - |
監査リスク
6
取締役会リスク
8
報酬リスク
2
株主権利リスク
2
パート2 · 株価と買い時
この部分は企業に価値があるかを判断するものではありません。ファンダメンタルズに納得したうえで、いつ買うかを選ぶためのものです。内容:テクニカル分析、ポテンシャル、過去のドローダウン、ガンマエクスポージャー。
Latest News
Recent headlines for AMGN, sourced from Markets Gazette.
- 6/3/2026NEUTRALThe CEO who loves AI autodidacts — and desperately needs his experts
Amgen Inc. is navigating the integration of Artificial Intelligence into its biotech operations, a strategic move initiated by CEO Bob Bradway. While the company is reportedly benefiting from early AI adoption, the article highlights internal challenges concerning the role and expertise of its scientific staff in this evolving landscape. The focus on AI adoption suggests potential for innovation and efficiency gains, but the internal debate about expert roles introduces a layer of operational complexity. Investors will monitor how Amgen balances AI advancements with its human capital strategy.
- 5/18/2026NEGATIVEAmgen Japanese Partner Urges Caution On Tavneos Use
Amgen's Japanese partner, Kissei Pharmaceutical, has urged physicians to halt new patient use of the autoimmune drug Tavneos in Japan. This advisory follows recent warnings from the U.S. Food and Drug Administration (FDA) regarding potential liver injuries associated with the drug. The recommendation also comes amid scrutiny over the clinical trial data supporting Tavneos. For Amgen investors, this development raises concerns about the drug's future market performance and potential regulatory hurdles in a key Asian market, potentially impacting future revenue streams.
- 4/22/2026POSITIVECongressional Trading Report: Rep. Maria Elvira Salazar Bought Over $221K In Amgen Stock
Representative Maria Elvira Salazar disclosed a purchase of Amgen Inc. stock valued between $221,000 and $500,000 on April 17th. This insider buying activity, particularly from a member of Congress, can be interpreted as a positive signal for the company's prospects. Amgen, a biotechnology giant, is involved in developing and manufacturing human therapeutics. Such investments by public officials often suggest confidence in the company's future performance and potential growth, which may influence investor sentiment and potentially lead to increased demand for the stock.
- 4/15/2026POSITIVE$1000 Invested In Amgen 15 Years Ago Would Be Worth This Much Today
An investment of $1000 in Amgen Inc. 15 years ago would have yielded a substantial return, highlighting the company's long-term growth trajectory and stock performance. While specific figures are not provided in the title, this narrative implies significant capital appreciation for shareholders over the past decade and a half. Such historical performance data is crucial for investors evaluating Amgen's potential for future returns, suggesting a track record of resilience and value creation in the biotechnology sector.
- 4/6/2026NEGATIVEAmgen Posts 77% Response In Thyroid Eye Disease Study
Amgen Inc. announced Phase 3 TEPEZZA OBI study results for thyroid eye disease, reporting a 77% response rate and significant proptosis reduction. Despite these clinically positive outcomes, the company's stock experienced a decline. This suggests that market sentiment may be reacting to factors beyond the immediate study results, potentially including broader market conditions, investor expectations regarding the drug's commercial potential, or concerns about the competitive landscape. Investors will be closely monitoring future developments and commercialization strategies.
- 4/3/2026POSITIVEIf You Invested $100 In Amgen Stock 15 Years Ago, You Would Have This Much Today
An investment of $100 in Amgen Inc. (AMGN) 15 years ago would have grown to approximately $570 today, representing a significant return on investment. This historical performance highlights Amgen's sustained growth and value creation over the long term. The biotech giant has consistently delivered on its pipeline and commercial execution, rewarding shareholders. For investors, this data point underscores Amgen's potential as a long-term wealth generator in the biotechnology sector, driven by innovation and market leadership.
- 3/31/2026NEGATIVEFDA Warns Of Fatal Liver Risks Linked To Amgen Tavneos Use
The U.S. Food and Drug Administration (FDA) has issued a warning regarding potential fatal liver risks associated with Amgen's drug Tavneos. The agency cited instances of drug-induced liver injury and rare complications, including vanishing bile duct syndrome. This development could lead to increased scrutiny, potential label changes, or even restrictions on Tavneos's use, impacting Amgen's revenue streams and investor confidence in its pharmaceutical pipeline. Investors will be monitoring any further guidance from the FDA and Amgen's response.
- 3/13/2026POSITIVEHere's How Much $100 Invested In Amgen 15 Years Ago Would Be Worth Today
An investment of $100 in Amgen Inc. 15 years ago would have grown to approximately $760 today, representing a substantial return on investment. This performance highlights Amgen's consistent growth and market position in the biotechnology sector over the past decade and a half. The company's ability to generate such returns suggests strong product pipelines, successful drug development, and effective market penetration. For investors, this historical data underscores Amgen's potential as a long-term growth stock, demonstrating resilience and value creation.
- 2/20/2026NEUTRALThe Analyst Verdict: Amgen In The Eyes Of 18 Experts
This article compiles analyst ratings for Amgen Inc. (AMGN) from February 2022, with multiple firms maintaining an 'Equal-Weight' rating. There is no new information or significant shift in recommendations to indicate immediate market direction for the stock.
via Markets Gazette